Patents

Active patents:

  1. Novel Coordination Complexes, and Methods for Preparing by Combinatorial Methods, Assaying and Using Same. Patent #6,806,289. October 19, 2004. MIT #8541.
  2. Fluorescent Metal Sensors, and Methods of Making and Using the Same. Shawn Burdette and Stephen J. Lippard. Patent #7,018,840. March 28, 2006. MIT #10027
  3. Fluorescein-Based Metal Sensors and Methods of Making and Using the Same. Shawn C. Burdette, Stephen J. Lippard, and Elizabeth M. Nolan. Patent #7,160,732. January 9, 2007. MIT #8910
  4. Sensors, And Methods Of Making And Using The Same. Stephen J. Lippard and Carolyn C. Woodroofe. Pate #7,399,639. July 15, 2008. MIT #10294
  5. Naphthoflurescein-Based Metal Sensors, And Methods Of Making And Using The Same. Christopher J. Chang, Stephen J. Lippard and Elizabeth M. Nolan. Patent #7,488,820. February 10, 2009. MIT # 10450
  6. Fluorescein Based Sensors For Tracking Nitric Oxide In Live Cells. Mi Hee Lim and Stephen J. Lippard. Patent #7,494,821. February 24, 2009. MIT #11806
  7. Fluorescein-Based Metal Sensors. Elizabeth M. Nolan and Stephen J. Lippard. Patent #7,615,377. November 10, 2009. MIT #10395
  8. Coordination Complexes, and Methods for Preparing by Combinatorial Meth- ods, Assaying and Using the Same. Christopher J. Ziegler and Stephen J. Lip- pard. Patent #7,651,979 B2. January 26, 2010. MIT #8541
  9. Sensors for Fluorescence and Magnetic Imaging Resonance Imaging. Xiao-An Zhang, Alan Pradip Jasanoff, Stephen J. Lippard. Patent #8,133,474 B2. March 13, 2012. MIT #12381
  10. Methods for Mobile Zinc Measurement. Stephen J. Lippard, Xiao-an Zhang, Zdravka Medarova, Anna Moore. Patent #8,574,914, November 5, 2013. MIT #13859.
  11. Nanostructures for Drug Delivery. Stephen J. Lippard, Shanta Dhar, Omid C. Farokhzad, Frank X. Gu, Nagesh Kolishetti. Patent #8,603,532, December 10, 2013. MIT #13405.
  12. Inhibitors of Bacterial Nitric Oxide Synthase, and Related Screening Methods. Lindsey E. McQuade, Evgeny Nudler. Patent #8,709,743 B2. April 29, 2014. MIT #12903J.
  13. Platinum Compounds as Treatment for Cancers, and Related Methods, Kits, and Compositions. Justin Wilson, Stephen J. Lippard. Patent #8,729,286 B2, May 20, 2014. MIT #15010.
  14. Functionalized Polymeric Nanoparticles as Vehicles for Targeted Delivery of Platinum Drugs. Shanta Dhar, Omid C. Farokhzad, Frank X. Gu, Nagesh Kolishetti, Stephen J. Lippard.  Patent #8,906,417 B2, Dec. 9, 2014. MIT #13405J.

Pending patents:

  1. Dual Mode Pharmaceutical Therapy. Shanta Dhar, Stephen J. Lippard. February 23, 2011. MIT#13271
  2. Highly Potent Monofunctional Platinum(II) Anticancer Agents, cDACP (Acroplatin) and Cdpncp (Phenanthroplatin). Ga Young Park, Stephen J. Lip- pard. June 21, 2011. MIT #14702
  3. Zinc Responsive Peptides. Robert J. Radford, Stephen J. Lippard. January 13, 2012. MIT #15316
  4. Soluble Nanoparticles as Delivery Systems for Prodrugs. Hongjie Dai, Rodney Feazell, Stephen J. Lippard. May 6, 2008. MIT #12688J
  5. Polyvalent Oligonucleotide Gold Nanoparticle Conjugates as Delivery Vehicles for Platinum(IV) Warheads. Weston L. Daniel, Shanta Dhar, David A. Giljo hann, Stephen J. Lippard, Chad A. Mirkin. September 1, 2010. MIT 13912J
  6. Functional Polylactide as a Dual Drug Delivery Platform for Targeted Cancer Chemotherapy. Shanta Dhar, Omid C. Farokhzad, Nagesh Kolishetti, Robert S. Langer, Stephen J. Lippard, Pedro M. Valencia. MIT 14034J

Patent in progress:

  1. Monofunctional Platinum Anticancer Agents, Including Quinoplatin. Stephen J. Lippard, Ga Young Park. Not filed. MIT #14576

Expired patents:

  1. Platinum-Intercalative Complexes for the Treatment of Cancer. Bruce Bowler and Stephen J. Lippard. Patent #4,843,161.  June 27, 1989. MIT #3891.
  2. Catalytic Enantioselective Addition of Hydrocarbon Equivalents to Alpha, Beta- Unsaturated Carbonyl Compounds. Kwang-hyun Ahn, Stephen J. Lippard, and Gilberto M. Villacorta.  Patent #4,962,214. October 9, 1990. MIT #4462.
  3. Reductive Coupling of Carbon Compounds via Transition Metal Complexes. Patricia A. Bianconi, Stephen J. Lippard, Chebolu P. Rao, Raymond N. Vrtis. Patent #5,026,884. June 25, 1991. MIT #4419.
  4. Enantioselective Addition of Hydrocarbons to Alpha, Beta-Unsaturated Car- bonyl Compounds. Kwang-hyun Ahn, Stephen J. Lipard, and Gilberto M. Vil- lacorta.  Patent #5,162,586. November 10, 1992, MIT #4462.
  5. Nucleic Acids Encoding DNA Structure-Specific Recognition Protein and Uses Thereof. Steven J. Brown, Suzanne L. Bruhn, Brian A. Donahue, John M. Es- sigmann, Patti J. Kellett, Stephen J. Lippard, Pieter M. Pil, and Jeffrey H. Toney. Patent #5,359,047. October 25, 1994. MIT #4787.
  6. Enantioselective Addition of Hydrocarbons to Alpha, Beta-Unsaturated Car- bonyl Compounds. Kwang-hyun Ahn, Stephen J. Lippard, and Gilberto M. Vil- lacorta.  Patent #5,440,062. August 8, 1995. MIT #4462.
  7. DNA Structure Specific Recognition Protein Complexes. Steven J. Brown, Suzanne L. Bruhn, Brian A. Donahue, John M. Essigmann, Patti J. Kellett, Ste- phen J. Lippard, Pieter M. Pil, and Jeffrey H. Toney.  Patent #5,670,621. Sep- tember 23, 1997. MIT #6701.
  8. Photo-Potentiation of Cisplatin Chemotherapy. Stefanie A. Kane and Stephen J. Lippard. Patent #6,030,783. February 29, 2000. MIT #6807.
  9. Uses for DNA Structure-Specific Recognition Protein. Steven J. Brown, Suzanne L. Bruhn, Brian A. Donahue, John M. Essigmann, Patti J. Kellett, Stephen J. Lippard, Pieter M. Pil, and Jeffrey H. Toney. Patent #6,475,791. November 5, 2002. MIT #6701
  10. Coordination Complexes Having Tethered Therapeutic Agents and/or Target- ing Moieties, and Methods of Making and Using the Same. Carmen M. Barnes, Ariel Haskel, Katie R. Barnes. Patent #7,138,520 B2. November 21, 2006. MIT #10066